A woman is trapped in her vehicle on the Western Highway just north of Pimpinio due to a crash.
Emergency services are directing traffic near Barbers Road, Wail.
Air Ambulance has been dispatched to the crash scene with Paramedics receiving the call at 9.20am.
Drivers should divert via Wallup to get around the closure, using Blue Ribbon Road and the Borung Highway, allowing extra time.